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Incomplete Assembly of the Dystrophin-Associated Protein Complex in 2D and 3D-Cultured Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM) are increasingly used to study genetic diseases on a human background. However, the lack of a fully mature adult cardiomyocyte phenotype of hiPSC-CM may be limiting the scope of these studies. Muscular dystrophies and concomitant...

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Detalles Bibliográficos
Autores principales: Gilbert, Guillaume, Kadur Nagaraju, Chandan, Duelen, Robin, Amoni, Matthew, Bobin, Pierre, Eschenhagen, Thomas, Roderick, H. Llewelyn, Sampaolesi, Maurilio, Sipido, Karin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599983/
https://www.ncbi.nlm.nih.gov/pubmed/34805146
http://dx.doi.org/10.3389/fcell.2021.737840