Delivery of IL-2 to the T Cell Surface Through Phosphatidylserine Permits Robust Expansion of CD8 T Cells

The phospholipid phosphatidylserine (PS) is naturally maintained on the cytoplasmic side of the plasma membrane. Independent of apoptosis, PS is redistributed to the surface of CD8 T cells in response to TCR-mediated activation. Annexin V (AnnV) is a protein known to bind PS with high affinity and h...

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Detalles Bibliográficos
Autores principales: MacDonald, Alana, Lam, Brandon, Lin, John, Ferrall, Louise, Kung, Yu Jui, Tsai, Ya Chea, Wu, T.-C., Hung, Chien-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599986/
https://www.ncbi.nlm.nih.gov/pubmed/34804041
http://dx.doi.org/10.3389/fimmu.2021.755995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599986/
https://www.ncbi.nlm.nih.gov/pubmed/34804041
http://dx.doi.org/10.3389/fimmu.2021.755995

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