Thrombospondin 2 Promotes IL-6 Production in Osteoarthritis Synovial Fibroblasts via the PI3K/AKT/NF-κB Pathway

BACKGROUND: It is known that osteoarthritis (OA) pathogenesis involves inflammation that drives pathologic changes and that the matricellular protein, thrombospondin-2 (TSP2), is involved in angiogenesis, carcinogenesis, and inflammation. However, how TSP2 contributes to OA inflammatory processes is...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Chun-Han, Tang, Chih-Hsin, Chen, Po-Chun, Liu, Ju-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600055/
https://www.ncbi.nlm.nih.gov/pubmed/34803392
http://dx.doi.org/10.2147/JIR.S314747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600055/
https://www.ncbi.nlm.nih.gov/pubmed/34803392
http://dx.doi.org/10.2147/JIR.S314747

Ejemplares similares