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Long-term immunogenicity and safety of a non-typeable Haemophilus influenzae-Moraxella catarrhalis vaccine: 4-year follow-up of a phase 1 multicentre trial

A multicomponent vaccine has been developed to reduce the frequency of acute exacerbations of COPD associated with non-typeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) infections, containing NTHi (PD and PE-PilA) and Mcat (UspA2) surface proteins. In a randomised, observer-bli...

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Detalles Bibliográficos
Autores principales: De Smedt, Philippe, Leroux-Roels, Geert, Vandermeulen, Corinne, Tasciotti, Annaelisa, Di Maro, Gennaro, Dozot, Marie, Casula, Daniela, Annaratone, Margherita, Riccucci, Daniele, Arora, Ashwani Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600057/
https://www.ncbi.nlm.nih.gov/pubmed/34820619
http://dx.doi.org/10.1016/j.jvacx.2021.100124