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ERK5 Inhibition Induces Autophagy-Mediated Cancer Cell Death by Activating ER Stress

Autophagy is a highly conserved intracellular process that preserves cellular homeostasis by mediating the lysosomal degradation of virtually any component of the cytoplasm. Autophagy is a key instrument of cellular response to several stresses, including endoplasmic reticulum (ER) stress. Cancer ce...

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Detalles Bibliográficos
Autores principales: Gámez-García, Andrés, Bolinaga-Ayala, Idoia, Yoldi, Guillermo, Espinosa-Gil, Sergio, Diéguez-Martínez, Nora, Megías-Roda, Elisabet, Muñoz-Guardiola, Pau, Lizcano, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600073/
https://www.ncbi.nlm.nih.gov/pubmed/34805151
http://dx.doi.org/10.3389/fcell.2021.742049