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Activation of Proneuronal Transcription Factor Ascl1 in Maternal Liver Ensures a Healthy Pregnancy

BACKGROUND & AIMS: Maternal liver shows robust adaptations to pregnancy to accommodate the metabolic needs of the developing and growing placenta and fetus by largely unknown mechanisms. We found that Ascl1, a gene encoding a basic helix-loop-helix transcription factor essential for neuronal dev...

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Detalles Bibliográficos
Autores principales: Lee, Joonyong, Garcia, Veronica, Nambiar, Shashank M., Jiang, Huaizhou, Dai, Guoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600092/
https://www.ncbi.nlm.nih.gov/pubmed/34438112
http://dx.doi.org/10.1016/j.jcmgh.2021.08.009