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Potential Role for Combined Subtype-Selective Targeting of M(1) and M(3) Muscarinic Receptors in Gastrointestinal and Liver Diseases

Despite structural similarity, the five subtypes comprising the cholinergic muscarinic family of G protein-coupled receptors regulate remarkably diverse biological functions. This mini review focuses on the closely related and commonly co-expressed M(1)R and M(3)R muscarinic acetylcholine receptor s...

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Detalles Bibliográficos
Autores principales: Tolaymat, Mazen, Sundel, Margaret H., Alizadeh, Madeline, Xie, Guofeng, Raufman, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600121/
https://www.ncbi.nlm.nih.gov/pubmed/34803723
http://dx.doi.org/10.3389/fphar.2021.786105