Epigallocatechin-3-gallate pretreatment alleviates doxorubicin-induced ferroptosis and cardiotoxicity by upregulating AMPKα2 and activating adaptive autophagy

Reports indicate that the mechanism of doxorubicin (Dox)-induced cardiotoxicity is very complex, involving multiple regulatory cell death forms. Furthermore, the clinical intervention effect is not ideal. Iron dependence, abnormal lipid metabolism, and excess reactive oxygen species generation, thre...

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Detalles Bibliográficos
Autores principales: He, Huan, Wang, Liang, Qiao, Yang, Yang, Bin, Yin, Dong, He, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600154/
https://www.ncbi.nlm.nih.gov/pubmed/34775319
http://dx.doi.org/10.1016/j.redox.2021.102185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600154/
https://www.ncbi.nlm.nih.gov/pubmed/34775319
http://dx.doi.org/10.1016/j.redox.2021.102185

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