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Assessment of Antibiotic De-escalation by Spectrum Score in Patients With Nosocomial Pneumonia: A Single-Center, Retrospective Cohort Study

BACKGROUND: Hospital-acquired and ventilator-associated pneumonia (HAP/VAP) cause significant mortality. Guidelines recommend empiric broad-spectrum antibiotics followed by de-escalation (DE). This study sought to assess the impact of DE on treatment failure. METHODS: This single-center retrospectiv...

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Detalles Bibliográficos
Autores principales: Ilges, Dan, Ritchie, David J, Krekel, Tamara, Neuner, Elizabeth A, Hampton, Nicholas, Kollef, Marin H, Micek, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600177/
https://www.ncbi.nlm.nih.gov/pubmed/34805436
http://dx.doi.org/10.1093/ofid/ofab508