Cargando…

Hippocampal Function Is Impaired by a Short-Term High-Fat Diet in Mice: Increased Blood–Brain Barrier Permeability and Neuroinflammation as Triggering Events

Worldwide, and especially in Western civilizations, most of the staple diets contain high amounts of fat and refined carbohydrates, leading to an increasing number of obese individuals. In addition to inducing metabolic disorders, energy dense food intake has been suggested to impair brain functions...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Paula, Gabriela Cristina, Brunetta, Henver S., Engel, Daiane F., Gaspar, Joana M., Velloso, Licio A., Engblom, David, de Oliveira, Jade, de Bem, Andreza Fabro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600238/ https://www.ncbi.nlm.nih.gov/pubmed/34803583 http://dx.doi.org/10.3389/fnins.2021.734158

Ejemplares similares

Impaired adult hippocampal neurogenesis in a mouse model of familial hypercholesterolemia: A role for the LDL receptor and cholesterol metabolism in adult neural precursor cells
por: Engel, Daiane F., et al.
Publicado: (2019)

Hypoxia Inducible Factor as a Central Regulator of Metabolism – Implications for the Development of Obesity
por: Gaspar, Joana M., et al.
Publicado: (2018)

Temporal Characterization of Behavioral and Hippocampal Dysfunction in the YAC128 Mouse Model of Huntington’s Disease
por: de Paula Nascimento-Castro, Cristine, et al.
Publicado: (2022)

High Cholesterol Diet Exacerbates Blood-Brain Barrier Disruption in LDLr–/– Mice: Impact on Cognitive Function
por: de Oliveira, Jade, et al.
Publicado: (2020)

Hypothalamic CREB Regulates the Expression of Pomc-Processing Enzyme Pcsk2
por: Zanesco, Ariane Maria, et al.
Publicado: (2022)

Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant system
por: Quispe, Ruth Liliám, et al.
Publicado: (2018)

Perivascular macrophages in high-fat diet-induced hypothalamic inflammation
por: Mendes, Natalia F., et al.
Publicado: (2022)

Energy homeostasis deregulation is attenuated by TUDCA treatment in streptozotocin-induced Alzheimer’s disease mice model
por: Zangerolamo, Lucas, et al.
Publicado: (2021)

Animal Models of Metabolic Disorders in the Study of Neurodegenerative Diseases: An Overview
por: de Bem, Andreza Fabro, et al.
Publicado: (2021)

Effect of Hypoproteic and High-Fat Diets on Hippocampal Blood-Brain Barrier Permeability and Oxidative Stress
por: de Aquino, Cristhyane Costa, et al.
Publicado: (2019)

SAT-149 The Metabolic Impairments Caused by Fructose and Prednisolone Intake Are Reversible After the Interruption of Exposure
por: Rafacho, Alex, et al.
Publicado: (2019)

We could be better if we ate better
por: Velloso, Licio A.
Publicado: (2020)

Nitric Oxide Released from Luminal S-Nitroso-N-Acetylcysteine Increases Gastric Mucosal Blood Flow
por: de Souza, Gabriela F. P., et al.
Publicado: (2015)

Strontium Attenuates Hippocampal Damage via Suppressing Neuroinflammation in High-Fat Diet-Induced NAFLD Mice
por: Wang, Shuai, et al.
Publicado: (2023)

Gliotoxin Aggravates Experimental Autoimmune Encephalomyelitis by Triggering Neuroinflammation
por: Fraga-Silva, Thais Fernanda de Campos, et al.
Publicado: (2019)

Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments
por: Reverchon, Flora, et al.
Publicado: (2020)

A Preclinical Model to Analyze the Oncological Safety of Fat Grafting in Breasts With Residual Cancer in Immunocompetent Hosts
por: Claro, Francisco, et al.
Publicado: (2020)

TLR4-interactor with leucine-rich repeats (TRIL) is involved in diet-induced hypothalamic inflammation
por: Moura-Assis, Alexandre, et al.
Publicado: (2021)

Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington's Disease
por: de Paula Nascimento-Castro, Cristine, et al.
Publicado: (2018)

The Obese Brain—Effects of Bariatric Surgery on Energy Balance Neurocircuitry
por: de Lima-Júnior, José Carlos, et al.
Publicado: (2015)

Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) in the Brain–Adipocyte Axis
por: Geloneze, Bruno, et al.
Publicado: (2017)

Unmanipulated native fat exposed to high-energy diet, but not autologous grafted fat by itself, may lead to overexpression of Ki67 and PAI-1
por: Claro, Francisco, et al.
Publicado: (2015)

COVID-19 induces neuroinflammation and loss of hippocampal neurogenesis
por: Klein, Robyn, et al.
Publicado: (2021)

Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis
por: Wu, Anbiao, et al.
Publicado: (2023)

Does Childhood Obesity Trigger Neuroinflammation?
por: Zingale, Valeria Domenica, et al.
Publicado: (2022)

Glutamic acid promotes hair growth in mice
por: Jara, Carlos Poblete, et al.
Publicado: (2021)

Lipid overload during gestation and lactation can independently alter lipid homeostasis in offspring and promote metabolic impairment after new challenge to high-fat diet
por: de Paula Simino, Laís Angélica, et al.
Publicado: (2017)

Activation of GPR40 induces hypothalamic neurogenesis through p38- and BDNF-dependent mechanisms
por: Engel, Daiane F., et al.
Publicado: (2020)

Fat and Protein Combat Triggers Immunological Weapons of Innate and Adaptive Immune Systems to Launch Neuroinflammation in Parkinson’s Disease
por: Hatton, Shelby Loraine, et al.
Publicado: (2022)

Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis
por: Bobbo, Vanessa C., et al.
Publicado: (2021)

TiO(2) Nanoparticles Induced Hippocampal Neuroinflammation in Mice
por: Ze, Yuguan, et al.
Publicado: (2014)

Hippocampal Neuroinflammation, Functional Connectivity, and Depressive Symptoms in Multiple Sclerosis
por: Colasanti, Alessandro, et al.
Publicado: (2016)

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging
por: Mangold, Colleen A., et al.
Publicado: (2017)

The differential response to neuronal hyperexcitation and neuroinflammation of the hippocampal neurogenic niche
por: Ruiz-Clavijo, Lorena, et al.
Publicado: (2023)

Autoimmune neuroinflammation triggers mitochondrial oxidation in oligodendrocytes
por: Steudler, Jasmin, et al.
Publicado: (2022)

Potential neuroprotective and anti-inflammatory effects provided by omega-3 (DHA) against Zika virus infection in human SH-SY5Y cells
por: Braz-De-Melo, Heloísa Antoniella, et al.
Publicado: (2019)

Dietary fats promote functional and structural changes in the median eminence blood/spinal fluid interface—the protective role for BDNF
por: Ramalho, Albina F., et al.
Publicado: (2018)

Metalloprotease Adam10 suppresses epilepsy through repression of hippocampal neuroinflammation
por: Zhu, Xinjian, et al.
Publicado: (2018)

Early effects of LPS-induced neuroinflammation on the rat hippocampal glycolytic pathway
por: Vizuete, Adriana Fernanda K., et al.
Publicado: (2022)

Choroid plexus enlargement is associated with neuroinflammation and reduction of blood brain barrier permeability in depression
por: Althubaity, Noha, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2ttfrerr7rma37jgutsduvl9u0