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Red blood cell blood group A antigen level affects the ability of heparin and PfEMP1 antibodies to disrupt Plasmodium falciparum rosettes

BACKGROUND: The histo-blood group ABO system has been associated with adverse outcomes in COVID-19, thromboembolic diseases and Plasmodium falciparum malaria. An integral part of the severe malaria pathogenesis is rosetting, the adherence of parasite infected red blood cells (RBCs) to uninfected RBC...

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Detalles Bibliográficos
Autores principales: Hedberg, Pontus, Sirel, Madle, Moll, Kirsten, Kiwuwa, Mpungu Steven, Höglund, Petter, Ribacke, Ulf, Wahlgren, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600353/
https://www.ncbi.nlm.nih.gov/pubmed/34794445
http://dx.doi.org/10.1186/s12936-021-03975-w