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KLF4, DAPK1 and SPG20 promoter methylation is not affected by DNMT1 silencing and hypomethylating drugs in lymphoma cells

Promoter methylation represents one of the major epigenetic mechanisms responsible for the regulation of gene expression. Hypomethylating drugs are currently approved for the treatment of myelodysplastic syndromes and acute myeloid leukemia, and some studies have recently been carried out on diffuse...

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Detalles Bibliográficos
Autores principales: Frazzi, Raffaele, Cusenza, Vincenza Ylenia, Pistoni, Mariaelena, Canovi, Laura, Cascione, Luciano, Bertoni, Francesco, Merli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600396/
https://www.ncbi.nlm.nih.gov/pubmed/34751409
http://dx.doi.org/10.3892/or.2021.8221