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Serotype-dependent recombinant adeno-associated vector (AAV) infection of Epstein–Barr virus-positive B-cells, towards recombinant AAV-based therapy of focal EBV + lymphoproliferative disorders

BACKGROUND: B-cell proliferative disorders, such as post-transplant lymphoproliferative disease (PTLD), are increased among persons afflicted by T-cell compromise. Most are Epstein–Barr virus (EBV) + and can first present with a focal lesion. Direct introduction of oncolytic viruses into localized t...

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Detalles Bibliográficos
Autores principales: Ahmadi, Elham, Ravanshad, Mehrdad, Xie, Jun, Panigrahi, Rajesh, Jubbal, Sandeep S., Guru, Santosh Kumar, Guangping, Gao, Ziyaeyan, Mazyar, Fingeroth, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600692/
https://www.ncbi.nlm.nih.gov/pubmed/34794463
http://dx.doi.org/10.1186/s12985-021-01695-w