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Multifaceted glycoadjuvant@AuNPs inhibits tumor metastasis through promoting T cell activation and remodeling tumor microenvironment

BACKGROUND: Cytosine-phosphate-guanine (CpG) dinucleotides has been used as adjuvants for cancer immunotherapy. However, unmodified CpG are not very efficient in clinical trials. Glucose, ligand of C-type lectin receptors (CLRs), can promote DC maturation and antigen presentation, which is the first...

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Detalles Bibliográficos
Autores principales: Xu, Xiaojing, Gan, Minfeng, Ge, Youzhen, Yi, Cheng, Feng, Tianyun, Liu, Mengjie, Wu, Cenhao, Chen, Xiang, Zhang, Weidong, Zhao, Lixiang, Zou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600715/
https://www.ncbi.nlm.nih.gov/pubmed/34794428
http://dx.doi.org/10.1186/s12951-021-01129-3