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Conditional deletion of ROCK2 induces anxiety-like behaviors and alters dendritic spine density and morphology on CA1 pyramidal neurons

Rho-associated kinase isoform 2 (ROCK2) is an attractive drug target for several neurologic disorders. A critical barrier to ROCK2-based research and therapeutics is the lack of a mouse model that enables investigation of ROCK2 with spatial and temporal control of gene expression. To overcome this,...

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Detalles Bibliográficos
Autores principales:	Weber, Audrey J., Adamson, Ashley B., Greathouse, Kelsey M., Andrade, Julia P., Freeman, Cameron D., Seo, Jung Vin, Rae, Rosaria J., Walker, Courtney K., Herskowitz, Jeremy H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600782/ https://www.ncbi.nlm.nih.gov/pubmed/34794469 http://dx.doi.org/10.1186/s13041-021-00878-4

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