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Nickel nanoparticle-induced cell transformation: involvement of DNA damage and DNA repair defect through HIF-1α/miR-210/Rad52 pathway

BACKGROUND: Nickel nanoparticles (Nano-Ni) are increasingly used in industry and biomedicine with the development of nanotechnology. However, the genotoxic and carcinogenic effects of Nano-Ni and the underlying mechanisms are still unclear. METHODS: At first, dose–response (0, 10, 20, and 30 μg/mL)...

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Detalles Bibliográficos
Autores principales: Mo, Yiqun, Zhang, Yue, Zhang, Yuanbao, Yuan, Jiali, Mo, Luke, Zhang, Qunwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600818/
https://www.ncbi.nlm.nih.gov/pubmed/34789290
http://dx.doi.org/10.1186/s12951-021-01117-7