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The immunotherapeutic role of indoleamine 2,3‐dioxygenase in head and neck squamous cell carcinoma: A systematic review

BACKGROUND: Novel cancer immunotherapy seeks to harness the body's own immune system and tip the balance in favour of antitumour activity. The intracellular enzyme indoleamine 2,3‐dioxygenase (IDO) is a critical regulator of the tumour microenvironment (TME) via tryptophan metabolism. The poten...

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Detalles Bibliográficos
Autores principales: Lin, Daniel J., Ng, James C. K., Huang, Lei, Robinson, Max, O’Hara, James, Wilson, Janet A., Mellor, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600953/
https://www.ncbi.nlm.nih.gov/pubmed/34053179
http://dx.doi.org/10.1111/coa.13794