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Mild repetitive head impacts alter perivascular flow in the midbrain dopaminergic system in awake rats

Head injury is a known risk factor for Parkinson’s disease. Disruption in the perivascular clearance of metabolic waste and unwanted proteins is thought to be a contributing factor to disease progression. We hypothesized that repetitive mild head impacts, without evidence of structural brain damage,...

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Detalles Bibliográficos
Autores principales: Cai, Xuezhu, Harding, Ian C, Sadaka, Aymen H, Colarusso, Bradley, Kulkarni, Praveen, Ebong, Eno, Qiao, Ju, O'Hare, Nick R, Ferris, Craig F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600963/
https://www.ncbi.nlm.nih.gov/pubmed/34806002
http://dx.doi.org/10.1093/braincomms/fcab265