Validation of a simple liquid chromatography coupled to tandem mass spectrometry method for the simultaneous determination of tacrolimus, sirolimus, everolimus and cyclosporin A in dried matrix on paper discs

INTRODUCTION: Due to its high specificity and sensitivity, liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is the gold standard method for immunosuppressant quantification in therapeutic drug monitoring. In this context, dried blood spots (DBS) have become a promising strategy a...

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Detalles Bibliográficos
Autores principales: Bressán, Ignacio Guillermo, Giménez, María Isabel, Llesuy, Susana Francisca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601012/
https://www.ncbi.nlm.nih.gov/pubmed/34820661
http://dx.doi.org/10.1016/j.jmsacl.2021.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601012/
https://www.ncbi.nlm.nih.gov/pubmed/34820661
http://dx.doi.org/10.1016/j.jmsacl.2021.01.003

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