Analysis of 2-methylcitric acid, methylmalonic acid, and total homocysteine in dried blood spots by LC-MS/MS for application in the newborn screening laboratory: A dual derivatization approach

Inborn errors of propionate, cobalamin and methionine metabolism are targets for Newborn Screening (NBS) in most programs world-wide, and are primarily screened by analyzing for propionyl carnitine (C3) and methionine in dried blood spot (DBS) cards using tandem mass spectrometry (MS/MS). Single-tie...

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Detalles Bibliográficos
Autores principales: Dubland, Joshua A., Rakić, Bojana, Vallance, Hilary, Sinclair, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601015/
https://www.ncbi.nlm.nih.gov/pubmed/34820666
http://dx.doi.org/10.1016/j.jmsacl.2021.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601015/
https://www.ncbi.nlm.nih.gov/pubmed/34820666
http://dx.doi.org/10.1016/j.jmsacl.2021.03.001

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