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Auxin‐mediated induction of GAL promoters by conditional degradation of Mig1p improves sesquiterpene production in Saccharomyces cerevisiae with engineered acetyl‐CoA synthesis

The yeast Saccharomyces cerevisiae uses the pyruvate dehydrogenase‐bypass for acetyl‐CoA biosynthesis. This relatively inefficient pathway limits production potential for acetyl‐CoA‐derived biochemical due to carbon loss and the cost of two high‐energy phosphate bonds per molecule of acetyl‐CoA. Her...

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Detalles Bibliográficos
Autores principales: Hayat, Irfan Farabi, Plan, Manuel, Ebert, Birgitta E., Dumsday, Geoff, Vickers, Claudia E., Peng, Bingyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601163/
https://www.ncbi.nlm.nih.gov/pubmed/34499421
http://dx.doi.org/10.1111/1751-7915.13880