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Auxin‐mediated induction of GAL promoters by conditional degradation of Mig1p improves sesquiterpene production in Saccharomyces cerevisiae with engineered acetyl‐CoA synthesis
The yeast Saccharomyces cerevisiae uses the pyruvate dehydrogenase‐bypass for acetyl‐CoA biosynthesis. This relatively inefficient pathway limits production potential for acetyl‐CoA‐derived biochemical due to carbon loss and the cost of two high‐energy phosphate bonds per molecule of acetyl‐CoA. Her...
Autores principales: | Hayat, Irfan Farabi, Plan, Manuel, Ebert, Birgitta E., Dumsday, Geoff, Vickers, Claudia E., Peng, Bingyin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601163/ https://www.ncbi.nlm.nih.gov/pubmed/34499421 http://dx.doi.org/10.1111/1751-7915.13880 |
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