Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage

SOS box of the recA promoter, P(VRecA) from Vibrio natriegens was characterized, cloned and expressed in a probiotic strain E. coli Nissle 1917. This promoter was then rationally engineered according to predicted interactions between LexA repressor and P(VRecA). The redesigned P(VRecA‐AT) promoter s...

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Detalles Bibliográficos
Autores principales: Chen, Jack X., Lim, Boon, Steel, Harrison, Song, Yizhi, Ji, Mengmeng, Huang, Wei E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601168/
https://www.ncbi.nlm.nih.gov/pubmed/33661573
http://dx.doi.org/10.1111/1751-7915.13767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601168/
https://www.ncbi.nlm.nih.gov/pubmed/33661573
http://dx.doi.org/10.1111/1751-7915.13767

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