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Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage
SOS box of the recA promoter, P(VRecA) from Vibrio natriegens was characterized, cloned and expressed in a probiotic strain E. coli Nissle 1917. This promoter was then rationally engineered according to predicted interactions between LexA repressor and P(VRecA). The redesigned P(VRecA‐AT) promoter s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601168/ https://www.ncbi.nlm.nih.gov/pubmed/33661573 http://dx.doi.org/10.1111/1751-7915.13767 |