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Micropatterning Transmission Electron Microscopy Grids to Direct Cell Positioning within Whole-Cell Cryo-Electron Tomography Workflows

Whole-cell cryo-electron tomography (cryo-ET) is a powerful technology that is used to produce nanometer-level resolution structures of macromolecules present in the cellular context and preserved in a near-native frozen-hydrated state. However, there are challenges associated with culturing and/or...

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Detalles Bibliográficos
Autores principales: Sibert, Bryan S., Kim, Joseph Y., Yang, Jie E., Wright, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601404/
https://www.ncbi.nlm.nih.gov/pubmed/34570100
http://dx.doi.org/10.3791/62992