β2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME

Myeloid-derived suppressor cells (MDSCs) impede antitumor immunity; however, the precise mechanisms that regulate their suppressive function remain unresolved. Identifying these mechanisms could lead to therapeutic interventions to boost cancer immunotherapy efficacy. Here, we reveal that β2 adrener...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohammadpour, Hemn, MacDonald, Cameron R., McCarthy, Philip L., Abrams, Scott I., Repasky, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601406/
https://www.ncbi.nlm.nih.gov/pubmed/34706232
http://dx.doi.org/10.1016/j.celrep.2021.109883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601406/
https://www.ncbi.nlm.nih.gov/pubmed/34706232
http://dx.doi.org/10.1016/j.celrep.2021.109883

Ejemplares similares