Cargando…

Down-regulation of cyclin D2 in amyloid β toxicity, inflammation, and Alzheimer’s disease

In the current study, we analyzed the effects of the systemic inflammatory response (SIR) and amyloid β (Aβ) peptide on the expression of genes encoding cyclins and cyclin-dependent kinase (Cdk) in: (i) PC12 cells overexpressing human beta amyloid precursor protein (βAPP), wild-type (APPwt-PC12), or...

Descripción completa

Detalles Bibliográficos
Autores principales: Czapski, Grzegorz A., Cieślik, Magdalena, Białopiotrowicz, Emilia, Lukiw, Walter J., Strosznajder, Joanna B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601534/
https://www.ncbi.nlm.nih.gov/pubmed/34793515
http://dx.doi.org/10.1371/journal.pone.0259740