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Down-regulation of cyclin D2 in amyloid β toxicity, inflammation, and Alzheimer’s disease
In the current study, we analyzed the effects of the systemic inflammatory response (SIR) and amyloid β (Aβ) peptide on the expression of genes encoding cyclins and cyclin-dependent kinase (Cdk) in: (i) PC12 cells overexpressing human beta amyloid precursor protein (βAPP), wild-type (APPwt-PC12), or...
Autores principales: | Czapski, Grzegorz A., Cieślik, Magdalena, Białopiotrowicz, Emilia, Lukiw, Walter J., Strosznajder, Joanna B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601534/ https://www.ncbi.nlm.nih.gov/pubmed/34793515 http://dx.doi.org/10.1371/journal.pone.0259740 |
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