Modulating mesendoderm competence during human germ layer differentiation

As pluripotent human embryonic stem cells progress toward one germ layer fate, they lose the ability to adopt alternative fates. Using a low-dimensional reaction coordinate to monitor progression toward ectoderm, we show that a differentiating stem cell’s probability of adopting a mesendodermal fate...

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Detalles Bibliográficos
Autores principales: Valcourt, James R., Huang, Roya E., Kundu, Sharmistha, Venkatasubramanian, Divya, Kingston, Robert E., Ramanathan, Sharad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601596/
https://www.ncbi.nlm.nih.gov/pubmed/34758327
http://dx.doi.org/10.1016/j.celrep.2021.109990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601596/
https://www.ncbi.nlm.nih.gov/pubmed/34758327
http://dx.doi.org/10.1016/j.celrep.2021.109990

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