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Computational redesign of a fluorogen activating protein with Rosetta

The use of unnatural fluorogenic molecules widely expands the pallet of available genetically encoded fluorescent imaging tools through the design of fluorogen activating proteins (FAPs). While there is already a handful of such probes available, each of them went through laborious cycles of in vitr...

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Detalles Bibliográficos
Autores principales: Bozhanova, Nina G., Harp, Joel M., Bender, Brian J., Gavrikov, Alexey S., Gorbachev, Dmitry A., Baranov, Mikhail S., Mercado, Christina B., Zhang, Xuan, Lukyanov, Konstantin A., Mishin, Alexander S., Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601599/
https://www.ncbi.nlm.nih.gov/pubmed/34748541
http://dx.doi.org/10.1371/journal.pcbi.1009555