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Computational redesign of a fluorogen activating protein with Rosetta
The use of unnatural fluorogenic molecules widely expands the pallet of available genetically encoded fluorescent imaging tools through the design of fluorogen activating proteins (FAPs). While there is already a handful of such probes available, each of them went through laborious cycles of in vitr...
Autores principales: | Bozhanova, Nina G., Harp, Joel M., Bender, Brian J., Gavrikov, Alexey S., Gorbachev, Dmitry A., Baranov, Mikhail S., Mercado, Christina B., Zhang, Xuan, Lukyanov, Konstantin A., Mishin, Alexander S., Meiler, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601599/ https://www.ncbi.nlm.nih.gov/pubmed/34748541 http://dx.doi.org/10.1371/journal.pcbi.1009555 |
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