Mutation Y453F in the spike protein of SARS-CoV-2 enhances interaction with the mink ACE2 receptor for host adaption

COVID-19 patients transmitted SARS-CoV-2 to minks in the Netherlands in April 2020. Subsequently, the mink-associated virus (miSARS-CoV-2) spilled back over into humans. Genetic sequences of the miSARS-CoV-2 identified a new genetic variant known as “Cluster 5” that contained mutations in the spike...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Wenlin, Lan, Jun, Ju, Xiaohui, Gong, Mingli, Long, Quanxin, Zhu, Zihui, Yu, Yanying, Wu, Jianping, Zhong, Jin, Zhang, Rong, Fan, Shilong, Zhong, Guocai, Huang, Ailong, Wang, Xinquan, Ding, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601601/
https://www.ncbi.nlm.nih.gov/pubmed/34748603
http://dx.doi.org/10.1371/journal.ppat.1010053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601601/
https://www.ncbi.nlm.nih.gov/pubmed/34748603
http://dx.doi.org/10.1371/journal.ppat.1010053

Ejemplares similares