SPARC Aggravates Blood-Brain Barrier Disruption via Integrin αVβ3/MAPKs/MMP-9 Signaling Pathway after Subarachnoid Hemorrhage

Blood-brain barrier (BBB) disruption is a common and critical pathology following subarachnoid hemorrhage (SAH). We investigated the BBB disruption property of secreted protein acidic and rich in cysteine (SPARC) after SAH. A total of 197 rats underwent endovascular perforation to induce SAH or sham...

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Detalles Bibliográficos
Autores principales: Okada, Takeshi, Suzuki, Hidenori, Travis, Zachary D., Altay, Orhan, Tang, Jiping, Zhang, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601826/
https://www.ncbi.nlm.nih.gov/pubmed/34804372
http://dx.doi.org/10.1155/2021/9739977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601826/
https://www.ncbi.nlm.nih.gov/pubmed/34804372
http://dx.doi.org/10.1155/2021/9739977

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