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TSH Combined with TSHR Aggravates Diabetic Peripheral Neuropathy by Promoting Oxidative Stress and Apoptosis in Schwann Cells

Subclinical hypothyroidism (SCH) is associated with diabetic peripheral neuropathy (DPN); however, the mechanism underlying this association remains unknown. This study is aimed at examining neurofunctional and histopathological alterations in a type 2 diabetes (T2DM) mouse model of SCH and investig...

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Detalles Bibliográficos
Autores principales: Fan, Jingwen, Pan, Qi, Gao, Qun, Li, Wenqing, Xiao, Fei, Guo, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601831/
https://www.ncbi.nlm.nih.gov/pubmed/34804362
http://dx.doi.org/10.1155/2021/2482453