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miR-17 acts as a tumor suppressor by negatively regulating the miR-17-92 cluster

Anaplastic thyroid cancer (ATC) is an aggressive, highly metastatic cancer that expresses high levels of the microRNA (miR)-17-92 cluster. We employ an miR inhibitor system to study the function of the different miRs within the miR-17-92 cluster based on seed sequence homology in the ATC SW579 cell...

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Detalles Bibliográficos
Autores principales: Sweat, Yan, Ries, Ryan J., Sweat, Mason, Su, Dan, Shao, Fan, Eliason, Steven, Amendt, Brad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601969/
https://www.ncbi.nlm.nih.gov/pubmed/34853714
http://dx.doi.org/10.1016/j.omtn.2021.10.021