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From single-target to cellular niche targeting in Crohn's disease: intercepting bad communications
The mainstay of moderate to severe Crohn's disease (CD), anti-TNF treatment, shows no clinical benefit in ∼40% of patients, likely due to incomplete cellular targeting and delayed treatment institution. While single-target therapeutics have been highly effective for some CD patients, substantia...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601974/ https://www.ncbi.nlm.nih.gov/pubmed/34773892 http://dx.doi.org/10.1016/j.ebiom.2021.103690 |