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Antisense oligonucleotides for Alzheimer's disease therapy: from the mRNA to miRNA paradigm
Alzheimer's disease (AD) represents a particular therapeutic challenge because its aetiology is very complex, with dynamic progression from preclinical to clinical stages. Several potential therapeutic targets and strategies were tested for AD, in over 2000 clinical trials, but no disease-modif...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602003/ https://www.ncbi.nlm.nih.gov/pubmed/34773891 http://dx.doi.org/10.1016/j.ebiom.2021.103691 |