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Antisense oligonucleotides for Alzheimer's disease therapy: from the mRNA to miRNA paradigm

Alzheimer's disease (AD) represents a particular therapeutic challenge because its aetiology is very complex, with dynamic progression from preclinical to clinical stages. Several potential therapeutic targets and strategies were tested for AD, in over 2000 clinical trials, but no disease-modif...

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Detalles Bibliográficos
Autores principales: Grabowska-Pyrzewicz, Wioleta, Want, Andrew, Leszek, Jerzy, Wojda, Urszula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602003/
https://www.ncbi.nlm.nih.gov/pubmed/34773891
http://dx.doi.org/10.1016/j.ebiom.2021.103691