Single-Cell Transcriptomic Analysis Revealed a Critical Role of SPP1/CD44-Mediated Crosstalk Between Macrophages and Cancer Cells in Glioma

High-grade glioma is one of the most lethal human cancers characterized by extensive tumor heterogeneity. In order to identify cellular and molecular mechanisms that drive tumor heterogeneity of this lethal disease, we performed single-cell RNA sequencing analysis of one high-grade glioma. According...

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Detalles Bibliográficos
Autores principales: He, Cong, Sheng, Luoyan, Pan, Deshen, Jiang, Shuai, Ding, Li, Ma, Xiaojun, Liu, Yaohua, Jia, Deshui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602110/
https://www.ncbi.nlm.nih.gov/pubmed/34805184
http://dx.doi.org/10.3389/fcell.2021.779319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602110/
https://www.ncbi.nlm.nih.gov/pubmed/34805184
http://dx.doi.org/10.3389/fcell.2021.779319

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