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DeepPhospho accelerates DIA phosphoproteome profiling through in silico library generation

Phosphoproteomics integrating data-independent acquisition (DIA) enables deep phosphoproteome profiling with improved quantification reproducibility and accuracy compared to data-dependent acquisition (DDA)-based phosphoproteomics. DIA data mining heavily relies on a spectral library that in most ca...

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Detalles Bibliográficos
Autores principales: Lou, Ronghui, Liu, Weizhen, Li, Rongjie, Li, Shanshan, He, Xuming, Shui, Wenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602247/
https://www.ncbi.nlm.nih.gov/pubmed/34795227
http://dx.doi.org/10.1038/s41467-021-26979-1