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Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children

Intermittent preventive treatment (IPT) with dihydroartemisinin-piperaquine (DP) is highly protective against malaria in children, but is not standard in malaria-endemic countries. Optimal DP dosing regimens will maximize efficacy and reduce toxicity and resistance selection. We analyze piperaquine...

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Detalles Bibliográficos
Autores principales: Wallender, Erika, Ali, Ali Mohamed, Hughes, Emma, Kakuru, Abel, Jagannathan, Prasanna, Muhindo, Mary Kakuru, Opira, Bishop, Whalen, Meghan, Huang, Liusheng, Duvalsaint, Marvin, Legac, Jenny, Kamya, Moses R., Dorsey, Grant, Aweeka, Francesca, Rosenthal, Philip J., Savic, Rada M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602248/
https://www.ncbi.nlm.nih.gov/pubmed/34795281
http://dx.doi.org/10.1038/s41467-021-27051-8