GOLM1 exacerbates CD8(+) T cell suppression in hepatocellular carcinoma by promoting exosomal PD-L1 transport into tumor-associated macrophages

The immunosuppressive microenvironment plays an important role in tumor progression and immunotherapy responses. Golgi membrane protein 1 (GOLM1) is correlated to hepatocellular carcinoma (HCC) progression and metastasis. However, little is known about the role of GOLM1 in regulating the immunosuppr...

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Detalles Bibliográficos
Autores principales: Chen, Jinhong, Lin, Zhifei, Liu, Lu, Zhang, Rui, Geng, Yan, Fan, Minghao, Zhu, Wenwei, Lu, Ming, Lu, Lu, Jia, Huliang, Zhang, Jubo, Qin, Lun-Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602261/
https://www.ncbi.nlm.nih.gov/pubmed/34795203
http://dx.doi.org/10.1038/s41392-021-00784-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602261/
https://www.ncbi.nlm.nih.gov/pubmed/34795203
http://dx.doi.org/10.1038/s41392-021-00784-0

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