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Follicular T cells are clonally and transcriptionally distinct in B cell-driven mouse autoimmune disease
Pathogenic autoantibodies contribute to tissue damage and clinical decline in autoimmune disease. Follicular T cells are central regulators of germinal centers, although their contribution to autoantibody-mediated disease remains unclear. Here we perform single cell RNA and T cell receptor (TCR) seq...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602266/ https://www.ncbi.nlm.nih.gov/pubmed/34795279 http://dx.doi.org/10.1038/s41467-021-27035-8 |