Safety and efficacy of thalidomide in patients with transfusion-dependent β-thalassemia: a randomized clinical trial

Thalidomide induces γ-globin expression in erythroid progenitor cells, but its efficacy on patients with transfusion-dependent β-thalassemia (TDT) remains unclear. In this phase 2, multi-center, randomized, double-blind clinical trial, we aimed to determine the safety and efficacy of thalidomide in...

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Detalles Bibliográficos
Autores principales: Chen, Jiang-Ming, Zhu, Wei-Jian, Liu, Jie, Wang, Gui-Zhen, Chen, Xiao-Qin, Tan, Yun, Xu, Wei-Wei, Qu, Li-Wei, Li, Jin-Yan, Yang, Huan-Ju, Huang, Lan, Cai, Ning, Wang, Wei-Da, Huang, Ken, Xu, Jian-Quan, Li, Guo-Hui, He, Sheng, Luo, Tian-Ying, Huang, Yi, Liu, Song-Hua, Wu, Wen-Qiang, Lu, Qi-Yang, Zhou, Mei-Guang, Chen, Shu-Ying, Li, Rong-Lan, Hu, Mei-Ling, Huang, Ying, Wei, Jin-Hua, Li, Jun-Min, Chen, Sai-Juan, Zhou, Guang-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602273/
https://www.ncbi.nlm.nih.gov/pubmed/34795208
http://dx.doi.org/10.1038/s41392-021-00811-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602273/
https://www.ncbi.nlm.nih.gov/pubmed/34795208
http://dx.doi.org/10.1038/s41392-021-00811-0

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