Combination of epigenetic regulation with gene therapy-mediated immune checkpoint blockade induces anti-tumour effects and immune response in vivo

Immunotherapy has become a powerful cancer treatment, but only a small fraction of patients have achieved durable benefits due to the immune escape mechanism. In this study, epigenetic regulation is combined with gene therapy-mediated immune checkpoint blockade to relieve this immune escape mechanis...

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Detalles Bibliográficos
Autores principales: Fang, Huapan, Guo, Zhaopei, Chen, Jie, Lin, Lin, Hu, Yingying, Li, Yanhui, Tian, Huayu, Chen, Xuesi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602287/
https://www.ncbi.nlm.nih.gov/pubmed/34795289
http://dx.doi.org/10.1038/s41467-021-27078-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602287/
https://www.ncbi.nlm.nih.gov/pubmed/34795289
http://dx.doi.org/10.1038/s41467-021-27078-x

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