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Combination of epigenetic regulation with gene therapy-mediated immune checkpoint blockade induces anti-tumour effects and immune response in vivo
Immunotherapy has become a powerful cancer treatment, but only a small fraction of patients have achieved durable benefits due to the immune escape mechanism. In this study, epigenetic regulation is combined with gene therapy-mediated immune checkpoint blockade to relieve this immune escape mechanis...
Autores principales: | Fang, Huapan, Guo, Zhaopei, Chen, Jie, Lin, Lin, Hu, Yingying, Li, Yanhui, Tian, Huayu, Chen, Xuesi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602287/ https://www.ncbi.nlm.nih.gov/pubmed/34795289 http://dx.doi.org/10.1038/s41467-021-27078-x |
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