Pre-existing immunity and vaccine history determine hemagglutinin-specific CD4 T cell and IgG response following seasonal influenza vaccination

Effectiveness of seasonal influenza vaccination varies between individuals and might be affected by vaccination history among other factors. Here we show, by monitoring frequencies of CD4 T cells specific to the conserved hemagglutinin epitope HA(118-132) and titres of IgG against the corresponding...

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Detalles Bibliográficos
Autores principales: Wild, Katharina, Smits, Maike, Killmer, Saskia, Strohmeier, Shirin, Neumann-Haefelin, Christoph, Bengsch, Bertram, Krammer, Florian, Schwemmle, Martin, Hofmann, Maike, Thimme, Robert, Zoldan, Katharina, Boettler, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602312/
https://www.ncbi.nlm.nih.gov/pubmed/34795301
http://dx.doi.org/10.1038/s41467-021-27064-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602312/
https://www.ncbi.nlm.nih.gov/pubmed/34795301
http://dx.doi.org/10.1038/s41467-021-27064-3

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