Cargando…

Pre-existing immunity and vaccine history determine hemagglutinin-specific CD4 T cell and IgG response following seasonal influenza vaccination

Effectiveness of seasonal influenza vaccination varies between individuals and might be affected by vaccination history among other factors. Here we show, by monitoring frequencies of CD4 T cells specific to the conserved hemagglutinin epitope HA(118-132) and titres of IgG against the corresponding...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wild, Katharina, Smits, Maike, Killmer, Saskia, Strohmeier, Shirin, Neumann-Haefelin, Christoph, Bengsch, Bertram, Krammer, Florian, Schwemmle, Martin, Hofmann, Maike, Thimme, Robert, Zoldan, Katharina, Boettler, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602312/ https://www.ncbi.nlm.nih.gov/pubmed/34795301 http://dx.doi.org/10.1038/s41467-021-27064-3

Ejemplares similares

Th1-Biased Hepatitis C Virus-Specific Follicular T Helper-Like Cells Effectively Support B Cells After Antiviral Therapy
por: Zoldan, Katharina, et al.
Publicado: (2021)

SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis
por: Boettler, Tobias, et al.
Publicado: (2022)

Follicular T Helper Cell Signatures in Primary Biliary Cholangitis and Primary Sclerosing Cholangitis
por: Adam, Leonie, et al.
Publicado: (2018)

Rapid and stable mobilization of CD8(+) T cells by SARS-CoV-2 mRNA vaccine
por: Oberhardt, Valerie, et al.
Publicado: (2021)

SARS-CoV-2-specific T-cell epitope repertoire in convalescent and mRNA-vaccinated individuals
por: Lang-Meli, Julia, et al.
Publicado: (2022)

Boosting compromised SARS-CoV-2-specific immunity with mRNA vaccination in liver transplant recipients
por: Luxenburger, Hendrik, et al.
Publicado: (2023)

COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation
por: Reinscheid, Matthias, et al.
Publicado: (2022)

Heterogeneity of HBV-Specific CD8(+) T-Cell Failure: Implications for Immunotherapy
por: Heim, Kathrin, et al.
Publicado: (2019)

Adaptive Immune Responses, Immune Escape and Immune-Mediated Pathogenesis during HDV Infection
por: Oberhardt, Valerie, et al.
Publicado: (2022)

Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions
por: Schwabenland, Marius, et al.
Publicado: (2021)

Ustekinumab Inhibits T Follicular Helper Cell Differentiation in Patients With Crohn’s Disease
por: Globig, Anna-Maria, et al.
Publicado: (2020)

TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection
por: Heim, Kathrin, et al.
Publicado: (2021)

Cross-Reactive Antibodies Binding to the Influenza Virus Subtype H11 Hemagglutinin
por: Strohmeier, Shirin, et al.
Publicado: (2019)

SARS-CoV-2-Specific T Cell Responses in Immunocompromised Individuals with Cancer, HIV or Solid Organ Transplants
por: Reeg, David B., et al.
Publicado: (2023)

Hepatitis B vaccine and NK cells: a new player in memory
por: Hofmann, Maike, et al.
Publicado: (2021)

HCV-Specific T Cell Responses During and After Chronic HCV Infection
por: Luxenburger, Hendrik, et al.
Publicado: (2018)

Administration of Multivalent Influenza Virus Recombinant Hemagglutinin Vaccine in Combination-Adjuvant Elicits Broad Reactivity Beyond the Vaccine Components
por: Hernandez-Davies, Jenny E., et al.
Publicado: (2021)

Mosaic Hemagglutinin-Based Whole Inactivated Virus Vaccines Induce Broad Protection Against Influenza B Virus Challenge in Mice
por: Liu, Yonghong, et al.
Publicado: (2021)

Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model
por: Amanat, Fatima, et al.
Publicado: (2019)

Chimeric Hemagglutinin-Based Live-Attenuated Vaccines Confer Durable Protective Immunity against Influenza A Viruses in a Preclinical Ferret Model
por: Liu, Wen-Chun, et al.
Publicado: (2021)

Magnitude and breadth of antibody cross-reactivity induced by recombinant influenza hemagglutinin trimer vaccine is enhanced by combination adjuvants
por: Hernandez-Davies, Jenny E., et al.
Publicado: (2022)

TCF1(+) hepatitis C virus-specific CD8(+) T cells are maintained after cessation of chronic antigen stimulation
por: Wieland, Dominik, et al.
Publicado: (2017)

Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8(+) T cells
por: Winkler, Frances, et al.
Publicado: (2023)

Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model
por: Stadlbauer, Daniel, et al.
Publicado: (2018)

H1 Hemagglutinin Priming Provides Long-Lasting Heterosubtypic Immunity against H5N1 Challenge in the Mouse Model
por: Carreño, Juan Manuel, et al.
Publicado: (2020)

Dissecting the hemagglutinin head and stalk-specific IgG antibody response in healthcare workers following pandemic H1N1 vaccination
por: Tete, Sarah M, et al.
Publicado: (2016)

Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice
por: Wang, Jiong, et al.
Publicado: (2018)

Pre-existing Hemagglutinin Stalk Antibodies Correlate with Protection of Lower Respiratory Symptoms in Flu-Infected Transplant Patients
por: Aydillo, Teresa, et al.
Publicado: (2020)

TLR agonists induce sustained IgG to hemagglutinin stem and modulate T cells following newborn vaccination
por: Clemens, Elene A., et al.
Publicado: (2022)

Chronische Hepatitis-B-Virusinfektion: aktuelle und zukünftige Therapieansätze
por: Neumann-Haefelin, Christoph, et al.
Publicado: (2022)

Role of Host Genetic Factors in the Outcome of Hepatitis C Virus Infection
por: Bengsch, Bertram, et al.
Publicado: (2009)

Non-sterilizing, Infection-Permissive Vaccination With Inactivated Influenza Virus Vaccine Reshapes Subsequent Virus Infection-Induced Protective Heterosubtypic Immunity From Cellular to Humoral Cross-Reactive Immune Responses
por: Choi, Angela, et al.
Publicado: (2020)

Plasma Cyclic Guanosine Monophosphate Is a Promising Biomarker of Clinically Significant Portal Hypertension in Patients With Liver Cirrhosis
por: Sturm, Lukas, et al.
Publicado: (2022)

The cyclophilin-inhibitor alisporivir stimulates antigen presentation thereby promoting antigen-specific CD8(+) T cell activation
por: Esser-Nobis, Katharina, et al.
Publicado: (2016)

Priming persistence of HCV
por: Schuch, Anita, et al.
Publicado: (2015)

Proton pump inhibitor treatment aggravates bacterial translocation in patients with advanced cirrhosis and portal hypertension
por: Sturm, Lukas, et al.
Publicado: (2023)

In the Shadow of Hemagglutinin: A Growing Interest in Influenza Viral Neuraminidase and Its Role as a Vaccine Antigen
por: Wohlbold, Teddy John, et al.
Publicado: (2014)

A CpG 1018 adjuvanted neuraminidase vaccine provides robust protection from influenza virus challenge in mice
por: Strohmeier, Shirin, et al.
Publicado: (2022)

Survival benefit of transarterial chemoembolization in patients with metastatic hepatocellular carcinoma: a single center experience
por: Bettinger, Dominik, et al.
Publicado: (2017)

Adaptive Immune Response against Hepatitis C Virus
por: Kemming, Janine, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0h96o5da9drm555s5a0bdki095