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Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism

Most cells in a developing organ stop proliferating when the organ reaches a correct, final size. The underlying molecular mechanisms are not understood. We find that in Drosophila the hormone ecdysone controls wing disc size. To study how ecdysone affects wing size, we inhibit endogenous ecdysone s...

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Detalles Bibliográficos
Autores principales: Strassburger, Katrin, Lutz, Marilena, Müller, Sandra, Teleman, Aurelio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602387/
https://www.ncbi.nlm.nih.gov/pubmed/34795214
http://dx.doi.org/10.1038/s41467-021-26780-0