Astrocytic ApoE underlies maturation of hippocampal neurons and cognitive recovery after traumatic brain injury in mice

Polymorphisms in the apolipoprotein E (ApoE) gene confer a major genetic risk for the development of late-onset Alzheimer’s disease (AD) and are predictive of outcome following traumatic brain injury (TBI). Alterations in adult hippocampal neurogenesis have long been associated with both the develop...

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Detalles Bibliográficos
Autores principales: Yu, Tzong-Shiue, Tensaouti, Yacine, Stephanz, Elizabeth P., Chintamen, Sana, Rafikian, Elizabeth E., Yang, Mu, Kernie, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602391/
https://www.ncbi.nlm.nih.gov/pubmed/34795427
http://dx.doi.org/10.1038/s42003-021-02841-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602391/
https://www.ncbi.nlm.nih.gov/pubmed/34795427
http://dx.doi.org/10.1038/s42003-021-02841-4

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