Cargando…

Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease

Peptide therapeutics are increasingly used in the treatment of disease, but their administration by injection reduces patient compliance and convenience, especially for chronic diseases. Thus, oral administration of a peptide therapeutic represents a significant advance in medicine, but is challenge...

Descripción completa

Detalles Bibliográficos
Autores principales: Pechenov, Sergei, Revell, Jefferson, Will, Sarah, Naylor, Jacqueline, Tyagi, Puneet, Patel, Chandresh, Liang, Lihuan, Tseng, Leo, Huang, Yue, Rosenbaum, Anton I., Balic, Kemal, Konkar, Anish, Grimsby, Joseph, Subramony, J. Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602401/
https://www.ncbi.nlm.nih.gov/pubmed/34795324
http://dx.doi.org/10.1038/s41598-021-01750-0